Lateralisation of subcortical functional connectivity during and after general anaesthesia.

ABSTRACT:

Background

Arousal and awareness are two important components of consciousness states. Functional neuroimaging has furthered our understanding of cortical and thalamocortical mechanisms of awareness. Investigating the relationship between subcortical functional connectivity and arousal has been challenging owing to the relatively small size of brainstem structures and thalamic nuclei, and their depth in the brain.

Methods

Resting state functional MRI scans of 72 healthy volunteers were acquired before, during, 1 h after, and 1 day after sevoflurane general anaesthesia. Functional connectivity of subcortical regions of interest vs whole brain and homotopic functional connectivity for assessment of left-right symmetry analyses of both cortical and subcortical regions of intere

SUBMITTER: Nir T 

PROVIDER: S-EPMC8787782 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature