Impact of intraventricular haemodynamic forces misalignment on left ventricular remodelling after myocardial infarction.

ABSTRACT:

Aims

Altered left ventricular (LV) haemodynamic forces (HDFs) have been associated with positive and negative remodelling after pathogenic or therapeutic events. We aimed to identify LV HDFs patterns associated with adverse LV remodelling (aLVr) in reperfused segment elevation myocardial infarction (STEMI) patients.

Methods and results

Forty-nine acute STEMI patients underwent cardiac magnetic resonance (CMR) at 1 week (baseline) and after 4 months (follow-up). LV HDFs were computed at baseline from cine CMR long axis data sets, using a novel technique based on endocardial boundary tracking, both in apex-base (A-B) and latero-septal (L-S) directions. HDFs distribution was evaluated by L-S over A-B HDFs ratio (L-S/A-B HDFs ratio %). HDFs parameters were computed over the enti

SUBMITTER: Filomena D 

PROVIDER: S-EPMC8787983 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature