N-terminal pro-B-type natriuretic peptide testing patterns in patients with heart failure with reduced ejection fraction.

ABSTRACT:

Aims

The N-terminal pro-B-type natriuretic peptide (NT-proBNP) is a commonly used biomarker in heart failure for diagnosis and prognostication. We aimed to determine the prevalence of NT-proBNP testing, distribution of NT-proBNP concentrations, and factors associated with receiving an NT-proBNP test in patients with heart failure with reduced ejection fraction (HFrEF), including the subset with a worsening heart failure event (WHFE).

Methods and results

This was a retrospective cohort study using two US databases: (i) the de-identified Humana Research Database between January 2015 and December 2018 and (ii) the Veradigm PINNACLE Registry^® between July 2013 and September 2017. We included adult patients with a confirmed diagnosis of HFrEF. In each data source, a su

SUBMITTER: Januzzi JL 

PROVIDER: S-EPMC8787988 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature