Clustering based on comorbidities in patients with chronic heart failure: an illustration of clinical diversity.

ABSTRACT:

Aims

It is increasingly recognized that the presence of comorbidities substantially contributes to the disease burden in patients with heart failure (HF). Several reports have suggested that clustering of comorbidities can lead to improved characterization of the disease phenotypes, which may influence management of the individual patient. Therefore, we aimed to cluster patients with HF based on medical comorbidities and their treatment and, subsequently, compare the clinical characteristics between these clusters.

Methods and results

A total of 603 patients with HF entering an outpatient HF rehabilitation programme were included [median age 65 years (interquartile range 56-71), 57% ischaemic origin of cardiomyopathy, and left ventricular ejection fraction 35% (26-45)]. Exer

SUBMITTER: Uszko-Lencer NHMK 

PROVIDER: S-EPMC8787997 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature