Dose of furosemide before admission predicts diuretic efficiency and long-term prognosis in acute heart failure.

ABSTRACT:

Aims

The outpatient diuretic dose is a marker of diuretic resistance and prognosis in chronic heart failure (HF). Still, the impact of the preadmission dose on diuretic efficiency (DE) and prognosis in acute HF is not fully known.

Methods and results

We conducted an observational and prospective study. All patients admitted for acute HF treated with intravenous diuretic and at least one criterion of congestion on admission were evaluated. Decongestion [physical examination, hemoconcentration, N-terminal pro-brain natriuretic peptide (NT-proBNP) change, and lung ultrasound], DE (weight loss and urine output per unit of 40 mg furosemide), and urinary sodium were monitored on the fifth day of admission. DE was dichotomized into high-low based on the median value. A multivariate

SUBMITTER: Blazquez-Bermejo Z 

PROVIDER: S-EPMC8788037 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature