Assessing the therapeutic potential of agomelatine, ramelteon, and melatonin against SARS-CoV-2.

ABSTRACT:

Background

The SARS-Cov-2(severe acute respiratory syndrome coronavirus 2) infection affecting human populations worldwide is now a very concerning issue considering the morbidity and mortality rates. Despite several measures followed by the medical fraternity and general public, there is no resolution. Therapeutic measures to tackle the infection have been based on researching new designer drug molecules that could prevent viral entry into the human host. Melatonin has been tried as an adjuvant in the management of COVID 19(coronavirus disease) illness but its specific antiviral role has not been investigated. Objectives: The objectives of the present study were to conduct an in-silico analysis to investigate if melatonin and related drugs namely ramelteon and agomelatine could be

SUBMITTER: Yadalam PK 

PROVIDER: S-EPMC8788135 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature