Patterns of piRNA Regulation in Drosophila Revealed through Transposable Element Clade Inference.

ABSTRACT: Transposable elements (TEs) are self-replicating "genetic parasites" ubiquitous to eukaryotic genomes. In addition to conflict between TEs and their host genomes, TEs of the same family are in competition with each other. They compete for the same genomic niches while experiencing the same regime of copy-number selection. This suggests that competition among TEs may favor the emergence of new variants that can outcompete their ancestral forms. To investigate the sequence evolution of TEs, we developed a method to infer clades: collections of TEs that share SNP variants and represent distinct TE family lineages. We applied this method to a panel of 85 Drosophila melanogaster genomes and found that the genetic variation of several TE families shows significant population structure that arise

SUBMITTER: Said I 

PROVIDER: S-EPMC8788220 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature