Chlamydia trachomatis infection in the genital tract is associated with inflammation and hypospermia in the infertile male of China.

ABSTRACT: Chlamydia trachomatis (CT) infection is the most prevalent sexually transmitted bacterial disease worldwide. However, unlike that in female infertility, the role of CT infection in male infertility remains controversial. The objective of this retrospective study was to explore the impacts of CT infection in the genital tract on sperm quality, sperm acrosin activity, antisperm antibody levels, and inflammation in a large cohort of infertile males in China. A total of 7154 semen samples were collected from infertile male subjects, 416 of whom were CT positive (CT+ group) and 6738 of whom were CT negative (CT- group), in our hospital between January 2016 and December 2018. Routine semen parameters (semen volume, pH, sperm concentration, viability, motility, morphology, etc.), granulocyte elas

SUBMITTER: Zhou H 

PROVIDER: S-EPMC8788609 | biostudies-literature | 2022 Jan-Feb

REPOSITORIES: biostudies-literature