Changes in the Distribution of Membrane Lipids during Growth of Thermotoga maritima at Different Temperatures: Indications for the Potential Mechanism of Biosynthesis of Ether-Bound Diabolic Acid (Membrane-Spanning) Lipids.

ABSTRACT: Membrane-spanning lipids are present in a wide variety of archaea, but they are rarely in bacteria. Nevertheless, the (hyper)thermophilic members of the order Thermotogales harbor tetraester, tetraether, and mixed ether/ester membrane-spanning lipids mostly composed of core lipids derived from diabolic acids, C₃₀, C₃₂, and C₃₄ dicarboxylic acids with two adjacent mid-chain methyl substituents. Lipid analysis of Thermotoga maritima across growth phases revealed a decrease of the relative abundance of fatty acids together with an increase of diabolic acids with independence of growth temperature. We also identified isomers of C₃₀ and C₃₂ diabolic acids, i.e., dicarboxylic acids with only one methyl group at C-15. Their distributio

SUBMITTER: Sahonero-Canavesi DX 

PROVIDER: S-EPMC8788747 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature