Diabetes and Risk of Sudden Death in Coronary Artery Disease Patients Without Severe Systolic Dysfunction.

ABSTRACT:

Objectives

This study sought to determine the absolute and relative associations of diabetes mellitus (DM) and hemoglobin A_1c (HbA_1c) with sudden and/or arrhythmic death (SAD) versus other modes of death in patients with coronary artery disease (CAD) who do not qualify for implantable cardioverter-defibrillators.

Background

Patients with CAD and DM are at elevated risk for SAD; however, it is unclear whether these patients would benefit from implantable cardioverter-defibrillators given competing causes of death and/or whether HbA_1c might augment SAD risk stratification.

Methods

In the PRE-DETERMINE study of 5,764 patients with CAD with left ventricular ejection fraction (LVEF) of >30% to 35%, competing risk analyses were used to compa

SUBMITTER: Venkateswaran RV 

PROVIDER: S-EPMC8788939 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature