Ontology highlight
ABSTRACT:
SUBMITTER: Tan S
PROVIDER: S-EPMC8789067 | biostudies-literature | 2022 Jan
REPOSITORIES: biostudies-literature
Tan Sujian S Huan Pin P Liu Baozhong B
Molecular biology and evolution 20220101 1
Although a conserved mechanism relying on BMP2/4 and Chordin is suggested for animal dorsal-ventral (DV) patterning, this mechanism has not been reported in spiralians, one of the three major clades of bilaterians. Studies on limited spiralian representatives have suggested markedly diverse DV patterning mechanisms, a considerable number of which no longer deploy BMP signaling. Here, we showed that BMP2/4 and Chordin regulate DV patterning in the mollusk Lottia goshimai, which was predicted in s ...[more]