Diverse mating phenotypes impact the spread of wtf meiotic drivers in Schizosaccharomyces pombe.

ABSTRACT: Meiotic drivers are genetic elements that break Mendel's law of segregation to be transmitted into more than half of the offspring produced by a heterozygote. The success of a driver relies on outcrossing (mating between individuals from distinct lineages) because drivers gain their advantage in heterozygotes. It is, therefore, curious that Schizosaccharomyces pombe, a species reported to rarely outcross, harbors many meiotic drivers. To address this paradox, we measured mating phenotypes in S. pombe natural isolates. We found that the propensity for cells from distinct clonal lineages to mate varies between natural isolates and can be affected both by cell density and by the available sexual partners. Additionally, we found that the observed levels of preferential mating bet

SUBMITTER: Lopez Hernandez JF 

PROVIDER: S-EPMC8789285 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature