Impaired Topographic Organization in Patients With Idiopathic Blepharospasm.

ABSTRACT: Background: Idiopathic blepharospasm (BSP) is a common adult-onset focal dystonia. Neuroimaging technology can be used to visualize functional and microstructural changes of the whole brain. Method: We used resting-state functional MRI (rs-fMRI) and graph theoretical analysis to explore the functional connectome in patients with BSP. Altogether 20 patients with BSP and 20 age- and gender-matched healthy controls (HCs) were included in the study. Measures of network topology were calculated, such as small-world parameters (clustering coefficient [C _p], the shortest path length [L _p]), network efficiency parameters (global efficiency [E _glob], local efficiency [E _loc]), and the nodal parameter (nodal effici

SUBMITTER: Hou Y 

PROVIDER: S-EPMC8791229 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature