Description of Bone Health Changes in a Cohort of Children With Acute Flaccid Myelitis (AFM).

ABSTRACT:

Objectives

To qualitatively describe bone health changes in children with acute flaccid myelitis (AFM) and assess relationships with muscle mass and strength and functional performance.

Methods

Retrospective analysis of a cohort of 79 children with AFM seen consecutively in one specialized academic center between January 1, 2007, and December 31, 2019.

Results

Of the 79 participants who were aged 4 months to 21 years old, 41 (52%) had bone density measured by dual energy absorptiometry (DXA) and 32 of them (78%) were diagnosed with low bone mass (LBM). We recorded 25 fractures that occurred after onset of neurologic deficit in 14 of the children in the cohort (18%). Lean muscle mass correlated with bone mass and functional performance as assessed by Physical Abilities

SUBMITTER: Curley N 

PROVIDER: S-EPMC8791422 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature