Risk for Reinfection After SARS-CoV-2: A Living, Rapid Review for American College of Physicians Practice Points on the Role of the Antibody Response in Conferring Immunity Following SARS-CoV-2 Infection.

ABSTRACT:

Background

The strength and duration of immunity from infection with SARS-CoV-2 are important for public health planning and clinical practice.

Purpose

To synthesize evidence on protection against reinfection after SARS-CoV-2 infection.

Data sources

MEDLINE (Ovid), the World Health Organization global literature database, ClinicalTrials.gov, COVID19reviews.org, and reference lists.

Study selection

Longitudinal studies that compared the risk for reinfection after SARS-CoV-2 infection versus infection risk in individuals with no prior infection.

Data extraction

Two investigators sequentially extracted study data and rated quality.

Data synthesis

Across 18 eligible studies, reinfection risk ranged from 0% to 2.2%. In persons with recent SARS-CoV-2 in

SUBMITTER: Helfand M 

PROVIDER: S-EPMC8791447 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature