Practice patterns and real-life outcomes for patients with acute promyelocytic leukemia in the United States.

ABSTRACT: Acute promyelocytic leukemia (APL) is associated with a favorable long-term prognosis if appropriate treatment is initiated promptly. Outcomes in clinical trials and population-based registries vary; potential explanations include a delay in treatment and lower adherence to guideline-recommended therapy in real-world practice. We used the Vizient Clinical Data Base to describe demographic characteristics, baseline clinical characteristics, and treatment patterns in patients newly diagnosed with APL during the study period of April 2017 to March 2020. Baseline white blood cell count was used to assign risk status and assess treatment concordance with National Comprehensive Cancer Network guidelines. Logistic regression models examined adjusted associations between patient, hospital, disease

SUBMITTER: Bewersdorf JP 

PROVIDER: S-EPMC8791583 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature