Altered executive control network connectivity in anti-NMDA receptor encephalitis.

ABSTRACT:

Objective

The goal of this study was to examine whether the static functional connectivity (FC) of the executive control network (ECN) and the temporal properties of dynamic FC states in the ECN can characterize the underlying nature of anti-N-methyl-d-aspartate (anti-NMDA) receptor encephalitis and their correlations with cognitive functions.

Methods

In total, 21 patients with anti-NMDA receptor encephalitis past the acute stage and 23 healthy controls (HCs) underwent a set of neuropsychological tests and participated in a resting-state fMRI study to analyse the static FC of the ECN and the temporal properties of dynamic FC states in the ECN. In addition, correlation analyses were performed to determine the correlations between the FC metrics and cognitive performance.

R

SUBMITTER: Chen Z 

PROVIDER: S-EPMC8791804 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature