Pathway engineering strategies for improved product yield in yeast-based industrial ethanol production.
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SUBMITTER: van Aalst ACA
PROVIDER: S-EPMC8792080 | biostudies-literature | 2022 Mar
REPOSITORIES: biostudies-literature
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Pathway engineering strategies for improved product yield in yeast-based industrial ethanol production.
van Aalst Aafke C A ACA de Valk Sophie C SC van Gulik Walter M WM Jansen Mickel L A MLA Pronk Jack T JT Mans Robert R
Synthetic and systems biotechnology 20220122 1
Product yield on carbohydrate feedstocks is a key performance indicator for industrial ethanol production with the yeast <i>Saccharomyces cerevisiae</i>. This paper reviews pathway engineering strategies for improving ethanol yield on glucose and/or sucrose in anaerobic cultures of this yeast by altering the ratio of ethanol production, yeast growth and glycerol formation. Particular attention is paid to strategies aimed at altering energy coupling of alcoholic fermentation and to strategies for ...[more]
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