Cerebral Small Vessel Disease and Depression Among Intracerebral Hemorrhage Survivors.

ABSTRACT:

Background and purpose

Intracerebral hemorrhage (ICH) is an acute manifestation of cerebral small vessel disease (CSVD), usually cerebral amyloid angiopathy or hypertensive arteriopathy. CSVD-related imaging findings are associated with increased depression incidence in the general population. Neuroimaging may, therefore, provide insight on depression risk among ICH survivors. We sought to determine whether CSVD CT and magnetic resonance imaging markers are associated with depression risk (before and after ICH), depression remission, and effectiveness of antidepressant treatment.

Methods

We analyzed data from the single-center longitudinal ICH study conducted at Massachusetts General Hospital. Participants underwent CT and magnetic resonance imaging imaging and were followed

SUBMITTER: Castello JP 

PROVIDER: S-EPMC8792169 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature