Blood Pressure and Glaucomatous Progression in a Large Clinical Population.

ABSTRACT:

Purpose

To investigate the effect of systemic arterial blood pressure (BP) on rates of progressive structural damage over time in glaucoma.

Design

Retrospective cohort study.

Participants

A total of 7501 eyes of 3976 subjects with glaucoma or suspected of glaucoma followed over time from the Duke Glaucoma Registry.

Methods

Linear mixed models were used to investigate the effects of BP on the rates of retinal nerve fiber layer (RNFL) loss from spectral-domain OCT (SD-OCT) over time. Models were adjusted for intraocular pressure (IOP), gender, race, diagnosis, central corneal thickness (CCT), follow-up time, and baseline disease severity.

Main outcome measure

Effect of mean arterial pressure (MAP), systolic arterial pressure (SAP), and diastolic arterial p

SUBMITTER: Jammal AA 

PROVIDER: S-EPMC8792171 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature