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Hair, serum and urine chromium levels in children with cognitive defects: A systematic review and meta-analysis of case control studies.


ABSTRACT: Environmental chromium exposure may cause impaired development of children. We conducted a systematic review and meta-analysis. Electronic databases including PubMed, Embase, Web of Science and CINAHL were searched to identify case-control studies that reported childhood Cr exposure and cognitive development. The Newcastle-Ottawa Scale (NOS) was used to ensure the quality of the included studies. Cr levels were compared in cases and controls, and a random effect meta-analysis was performed using Stata version 16. Twelve of 61 studies identified in the literature search were eligible for this analysis. Hair, serum and urine Cr measurements were reported by seven, two and one studies, respectively. In addition, one study reported both serum and hair Cr exposure and another reported urine and

SUBMITTER: Islam GMR 

PROVIDER: S-EPMC8792285 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature