Outcomes in patients receiving palliative chemotherapy for advanced biliary tract cancer.

ABSTRACT:

Background & aims

Advanced biliary tract cancer (ABTC) is associated with a poor prognosis. Real-world data on the outcome of patients with ABTC undergoing sequential chemotherapies remain scarce, and little is known about treatment options beyond the established first- and second-line treatments with gemcitabine + cisplatin and FOLFOX. This study aimed to evaluate the outcome of patients with regard to different oncological therapies and to identify prognostic factors.

Methods

From January 2010 until December 2019, 142 patients started palliative chemotherapy at our tertiary care liver center. Overall survival (OS) was calculated using Kaplan-Meier plots. Prognostic factors were evaluated using cox proportional-hazards.

Results

Patients received a median number of 2

SUBMITTER: Thol F 

PROVIDER: S-EPMC8792293 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature