Personal history of autoimmune disease and other medical conditions and risk of myelodysplastic syndromes.

ABSTRACT:

Background

Autoimmune diseases and hematopoietic malignancies are known to cluster within individuals, suggesting intertwined etiologies. A limited number of studies have evaluated pre-existing medical conditions as risk factors for myelodysplastic syndromes (MDS). We evaluated associations between autoimmune disease and other medical conditions and risk of MDS.

Methods

Cases were identified through the Minnesota Cancer Reporting System. Controls were identified through the Minnesota State driver's license/identification card list. History of autoimmune disease and other medical conditions was based on self-report; proxy interviews were not conducted. Unconditional logistic regression was used to calculate adjusted odds ratios (aORs) and 95% confidence intervals (CI).

Res

SUBMITTER: Linabery AM 

PROVIDER: S-EPMC8792352 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature