Primary central nervous system lymphoma in the United States, 1975-2017.

ABSTRACT:

Background

Primary central nervous system lymphoma (PCNSL) has received more attention because of an inferior prognosis. Less is known about the incidence rate, histological type, and survival rate of PCNSL, especially in the 2010s.

Methods

Data of PCNSL from the Surveillance, Epidemiology, and End Results (SEER) registry database (SEER 9 registries and SEER 18 registries) were used. Incidence was estimated by age, gender, race, site, and histological type. Trends were analyzed using joinpoint regression and described as annual percent change (APC) and average annual percent change (AAPC). Five-year overall survival estimates were compared using log-rank tests.

Results

Most PCNSL occurred in the brain, followed by the spinal cord. The most frequent histological type o

SUBMITTER: Lv C 

PROVIDER: S-EPMC8793121 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature