Malaria hospitalisation in East Africa: age, phenotype and transmission intensity.

ABSTRACT:

Background

Understanding the age patterns of disease is necessary to target interventions to maximise cost-effective impact. New malaria chemoprevention and vaccine initiatives target young children attending routine immunisation services. Here we explore the relationships between age and severity of malaria hospitalisation versus malaria transmission intensity.

Methods

Clinical data from 21 surveillance hospitals in East Africa were reviewed. Malaria admissions aged 1 month to 14 years from discrete administrative areas since 2006 were identified. Each site-time period was matched to a model estimated community-based age-corrected parasite prevalence to provide predictions of prevalence in childhood (PfPR_2-10). Admission with all-cause malaria, severe malaria ana

SUBMITTER: Kamau A 

PROVIDER: S-EPMC8793189 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature