Validation of the automated neuropsychological assessment metrics for assessing cognitive impairment in systemic lupus erythematosus.

ABSTRACT:

Objective

We previously demonstrated the utility of the Automated Neuropsychological Assessment Metrics (ANAM) for screening cognitive impairment (CI) in patients with systemic lupus erythematosus (SLE) and developed composite indices for interpreting ANAM results. Our objectives here were to provide further support for the ANAM's concurrent criterion validity against the American College of Rheumatology neuropsychological battery (ACR-NB), identify the most discriminatory subtests and scores of the ANAM for predicting CI, and provide a new approach to interpret ANAM results using Classification and Regression Tree (CART) analysis.

Methods

300 adult SLE patients completed an adapted ACR-NB and ANAM on the same day. As per objectives, six models were built using combinations

SUBMITTER: Yuen K 

PROVIDER: S-EPMC8793300 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature