Ontology highlight
ABSTRACT:
SUBMITTER: Luna M
PROVIDER: S-EPMC8793322 | biostudies-literature | 2021 Sep
REPOSITORIES: biostudies-literature
Luna Marysol M Guss Jason D JD Vasquez-Bolanos Laura S LS Castaneda Macy M Rojas Manuela Vargas MV Strong Jasmin M JM Alabi Denise A DA Dornevil Sophie D SD Nixon Jacob C JC Taylor Erik A EA Donnelly Eve E Fu Xueyan X Shea M Kyla MK Booth Sarah L SL Bicalho Rodrigo R Hernandez Christopher J CJ
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20210604 9
Modifications to the constituents of the gut microbiome influence bone density and tissue-level strength, but the specific microbial components that influence tissue-level strength in bone are not known. Here, we selectively modify constituents of the gut microbiota using narrow-spectrum antibiotics to identify components of the microbiome associated with changes in bone mechanical and material properties. Male C57BL/6J mice (4 weeks) were divided into seven groups (n = 7-10/group) and had taxa ...[more]