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Enhancing Autonomy in Biobank Decisions: Too Much of a Good Thing?

ABSTRACT: The opportunity to receive individual research results (IRRs) in accordance with personal preferences may incentivize biobank participation and maximize perceived benefit. This trial investigated the relationship between parents' preferences and intent to participate (ITP) in biobank research utilizing their child's genetic information. We randomized parents of pediatric patients to four hypothetical biobanks, one of which employed a preference-setting model for return of results regarding their child. ITP was highest among those desiring all types of IRRs (93.3%) and decreased as participants became increasingly selective with their preferences ( p < .0001). We demonstrated that most parents would participate in a biobank that allows for preference setting; however, those who set preferences to receive a narrower set of IRRs are less likely to participate.

SUBMITTER: Mitchell PB

PROVIDER: S-EPMC8793343 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature

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Enhancing Autonomy in Biobank Decisions: Too Much of a Good Thing?

Mitchell Phoebe B PB Ziniel Sonja I SI Savage Sarah K SK Christensen Kurt D KD Weitzman Elissa R ER Green Robert C RC Huntington Noelle L NL Mathews Debra J DJ Holm Ingrid A IA

Journal of empirical research on human research ethics : JERHRE 20180223 2

The opportunity to receive individual research results (IRRs) in accordance with personal preferences may incentivize biobank participation and maximize perceived benefit. This trial investigated the relationship between parents' preferences and intent to participate (ITP) in biobank research utilizing their child's genetic information. We randomized parents of pediatric patients to four hypothetical biobanks, one of which employed a preference-setting model for return of results regarding their ...[more]

PMID: 29471711

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Enhancing Autonomy in Biobank Decisions: Too Much of a Good Thing?

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Enhancing Autonomy in Biobank Decisions: Too Much of a Good Thing?

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