Measuring Digital Pathology Throughput and Tissue Dropouts.

ABSTRACT:

Background

Digital pathology operations that precede viewing by a pathologist have a substantial impact on costs and fidelity of the digital image. Scan time and file size determine throughput and storage costs, whereas tissue omission during digital capture ("dropouts") compromises downstream interpretation. We compared how these variables differ across scanners.

Methods

A 212 slide set randomly selected from a gynecologic-gestational pathology practice was used to benchmark scan time, file size, and image completeness. Workflows included the Hamamatsu S210 scanner (operated under default and optimized profiles) and the Leica GT450. Digital tissue dropouts were detected by the aligned overlay of macroscopic glass slide camera images (reference) with images created by the sl

SUBMITTER: Mutter GL 

PROVIDER: S-EPMC8794031 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature