Modifiable lifestyle factors and cognitive reserve: A systematic review of current evidence.

ABSTRACT: This systematic review aims to summarize cognitive reserve (CR) evaluation approaches and to examine the role of seven selected modifiable lifestyle factors (diet, smoking, alcohol consumption, physical activity, cognitive leisure activity, sleep, and meditation) in mitigating the impacts of age- or disease-related brain changes on cognition. Eighteen population-based English empirical studies were included. We summarize the study designs and identify three CR models that were broadly used in these studies, including a residual model assessing lifestyle factors in relation to unexplained variance in cognition after accounting for brain markers, a moderation model testing whether lifestyle factors moderate the relationship between brain status and cognition, and a controlling model examinin

SUBMITTER: Song S 

PROVIDER: S-EPMC8794051 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature