Relationship between adiponectin multimer levels and subtypes of cerebral infarction.

ABSTRACT:

Aim

Serum adiponectin levels are decreased in patients with cerebral infarction. Adiponectin in circulation exists in three isoforms: high molecular weight (HMW), medium molecular weight (MMW), and low molecular weight (LMW) adiponectin. We measured serum levels of total adiponectin and adiponectin multimers (HMW, MMW, and LMW) in patients with cerebral infarction and compared the serum levels of the three adiponectin multimers in stroke subtypes. We also evaluated the clinical value of adiponectin multimer levels as a biomarker for cerebral infarction.

Methods

We assessed a total of 132 patients with cerebral infarctions. The serum levels of total and adiponectin multimers were measured using enzyme-linked immunosorbent assay (ELISA).

Results

The total and HMW adipon

SUBMITTER: Tagawa N 

PROVIDER: S-EPMC8794129 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature