Pan-cancer analysis indicates that MYBL2 is associated with the prognosis and immunotherapy of multiple cancers as an oncogene.
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ABSTRACT:
SUBMITTER: Chen X
PROVIDER: S-EPMC8794527 | biostudies-literature | 2021 Nov
REPOSITORIES: biostudies-literature
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Pan-cancer analysis indicates that MYBL2 is associated with the prognosis and immunotherapy of multiple cancers as an oncogene.
Chen Xingjie X Lu Yalin Y Yu Hao H Du Kangjie K Zhang Yu Y Nan Yang Y Huang Qiang Q
Cell cycle (Georgetown, Tex.) 20210929 21
MYBL2 has been demonstrated to be an oncogene in some cancers, but there is no pan-cancer analysis at the macro level. We used multiple online or offline bioinformatic tools to examine the effects of MYBL2 in human cancers. We first identified that MYBL2 was highly expressed and related to the stage and grade of most cancers. The results of survival analysis from two databases showed that high MYBL2 expression was positively correlated with a poor prognosis for most cancer patients. We observed ...[more]
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