Impact of Fatty Acids on Obesity-Associated Diseases and Radical Weight Reduction.

ABSTRACT:

Purpose

Fatty acids (FA), particularly polyunsaturated (PUFA) ones, are involved in the regulation of glycemic control, lipid metabolism, and inflammation. The aim of the study was to assess patient FA profile in relation to obesity, lipid and carbohydrate metabolism disturbances, and weight loss.

Materials and methods

The studied group consisted of 51 patients with extreme obesity, 23 of whom achieved radical weight reduction within 1 year after a laparoscopic sleeve gastrectomy (LSG). FA levels were determined using gas chromatography with flame ionization detection.

Results

Patients with extreme obesity and higher serum PUFA content have lower serum levels of SFA and MUFA (especially myristic, palmitic, lignoceric acids and palmitoleic, oleic acids), as well as low

SUBMITTER: Wrzosek M 

PROVIDER: S-EPMC8794933 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature