Association of oral contraceptives and tubal ligation with antimullerian hormone.

ABSTRACT:

Objective

Oral contraceptives (OCs) and tubal ligation are commonly used methods of contraception that may impact ovarian function. Few studies have examined the association of these factors with antimüllerian hormone (AMH), a marker of ovarian aging.

Methods

We examined the association of OC use and tubal ligation with AMH in the Nurses' Health Study II prospective cohort among a subset of 1,420 premenopausal participants who provided a blood sample in 1996-1999. History of OC use and tubal ligation were reported in 1989 and updated every 2 years until blood collection. We utilized generalized linear models to assess whether mean AMH levels varied by duration of and age at first use of OCs and history, age, and type of tubal ligation.

Results

In multivariable models

SUBMITTER: Langton CR 

PROVIDER: S-EPMC8795476 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature