Potential Association Between Changes in Microbiota Level and Lung Diseases: A Meta-Analysis.

ABSTRACT:

Objective

Lung microbiota is increasingly implicated in multiple types of respiratory diseases. However, no study has drawn a consistent conclusion regarding the relationship between changes in the microbial community and lung diseases. This study verifies the association between microbiota level and lung diseases by performing a meta-analysis.

Methods

Literature databases, including PubMed, ISI Web of Science, Embase, Google Scholar, PMC, and CNKI, were used to collect related articles published before March 20, 2021. The standard mean deviation (SMD) and related 95% confidence intervals (CIs) were calculated using a random-effects model. Subgroup, sensitivity, and publication bias analyses were also conducted.

Results

Six studies, comprising 695 patients with lung d

SUBMITTER: Chai L 

PROVIDER: S-EPMC8795898 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature