Progress, evolving therapeutic/diagnostic approaches, and challenges in the management of hepatitis C virus infections.

ABSTRACT: Hepatitis C virus (HCV) infections are emerging as one of the foremost challenges in healthcare owing to its chronicity and the virus's quasispecies nature. Worldwide, over 170 million people are chronically infected with HCV, with an annual mortality of over 500,000 people across the world. The emerging pathophysiological evidence links HCV infections to a risk of developing liver diseases such as cirrhosis and hepatocellular carcinoma. Despite the great strides that have been made towards understanding the pathophysiology of disease progression, the tailored treatments of HCV infection remain to be established. The present review provides an update of the literature pertaining to evolving therapeutic approaches and prophylactic measures for the effective management of HCV infections. An

SUBMITTER: Meshram RJ 

PROVIDER: S-EPMC8795940 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature