Investigating Toxin Diversity and Abundance in Snake Venom Proteomes.

ABSTRACT: Understanding snake venom proteomes is becoming increasingly important to understand snake venom biology, evolution and especially clinical effects of venoms and approaches to antivenom development. To explore the current state of snake venom proteomics and transcriptomics we investigated venom proteomic methods, associations between methodological and biological variability and the diversity and abundance of protein families. We reviewed available studies on snake venom proteomes from September 2017 to April 2021. This included 81 studies characterising venom proteomes of 79 snake species, providing data on relative toxin abundance for 70 species and toxin diversity (number of different toxins) for 37 species. Methodologies utilised in these studies were summarised and compared. Several c

SUBMITTER: Tasoulis T 

PROVIDER: S-EPMC8795951 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature