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The influence of vitamin D supplementation on local and systemic inflammatory markers in periodontitis patients: A pilot study.


ABSTRACT:

Objectives

Vitamin D deficiency/insufficiency is a worldwide public health issue that has been linked to numerous inflammatory disorders, including periodontitis. There is increasing support for a role for adequate vitamin D levels in overall health. Populations with darker skin color have a higher prevalence of vitamin D deficiency/insufficiency and periodontitis. The purpose of this small pilot study was to investigate the influence of 12 weeks of 25(OH)D vitamin D supplementation (VDS) on mediators of systemic inflammation in dark-skinned, periodontitis patients.

Materials and methods

A total of 23 patients with moderate to severe periodontitis were randomly assigned to the vitamin D group or placebo group and received intensive single visit scaling and root planning to e

SUBMITTER: Meghil MM 

PROVIDER: S-EPMC8796207 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature