COBREXA.jl: constraint-based reconstruction and exascale analysis.
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ABSTRACT:
SUBMITTER: Kratochvil M
PROVIDER: S-EPMC8796381 | biostudies-literature | 2021 Nov
REPOSITORIES: biostudies-literature
Publications
COBREXA.jl: constraint-based reconstruction and exascale analysis.
Kratochvíl Miroslav M Heirendt Laurent L Wilken St Elmo SE Pusa Taneli T Arreckx Sylvain S Noronha Alberto A van Aalst Marvin M Satagopam Venkata P VP Ebenhöh Oliver O Schneider Reinhard R Trefois Christophe C Gu Wei W
Bioinformatics (Oxford, England) 20220101 4
<h4>Summary</h4>COBREXA.jl is a Julia package for scalable, high-performance constraint-based reconstruction and analysis of very large-scale biological models. Its primary purpose is to facilitate the integration of modern high performance computing environments with the processing and analysis of large-scale metabolic models of challenging complexity. We report the architecture of the package, and demonstrate how the design promotes analysis scalability on several use-cases with multi-organism ...[more]
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