Moderate physical activity may not decrease the risk of cardiovascular disease in persistently overweight and obesity adults.

ABSTRACT:

Background

Body mass index (BMI) and physical activity (PA) has been documented to be associated with cardiovascular disease (CVD). However, the evidences regarding joint phenotypes of BMI and PA trajectories with risk for CVD and all-cause mortality are still limited.

Methods

Participants from the Kailuan Study, followed up during 2006-2019 were included, with primary outcomes of CVDs (myocardial infarction or stroke) and all-cause mortality. BMI and PA were repeatedly measured at least three times, and thus joint phenotypes trajectory groups were identified by group-based trajectory modeling. Cox proportional hazards models were used to examine the associations between trajectory groups and CVDs and all-cause mortality.

Results

Totally 88,141 (6 trajectories) and 89

SUBMITTER: Tian Q 

PROVIDER: S-EPMC8796584 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature