Cation enrichment in the ion atmosphere is promoted by local hydration of DNA.

ABSTRACT: Electrostatic interactions are central to the structure and function of nucleic acids, including their folding, condensation, and interaction with proteins and other charged molecules. These interactions are profoundly affected by ions surrounding nucleic acids, the constituents of the so-called ion atmosphere. Here, we report precise Fourier Transform-Terahertz/Far-Infrared (FT-THz/FIR) measurements in the frequency range 30-500 cm^-1 for a 24-bp DNA solvated in a series of alkali halide (NaCl, NaF, KCl, CsCl, and CsF) electrolyte solutions which are sensitive to changes in the ion atmosphere. Cation excess in the ion atmosphere is detected experimentally by observation of cation modes of Na⁺, K⁺, and Cs⁺ in the frequency range between 70-90 cm

SUBMITTER: Ma CY 

PROVIDER: S-EPMC8797164 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature