Repeated origins, widespread gene flow, and allelic interactions of target-site herbicide resistance mutations.

ABSTRACT: Causal mutations and their frequency in agricultural fields are well-characterized for herbicide resistance. However, we still lack understanding of their evolutionary history: the extent of parallelism in the origins of target-site resistance (TSR), how long these mutations persist, how quickly they spread, and allelic interactions that mediate their selective advantage. We addressed these questions with genomic data from 19 agricultural populations of common waterhemp (Amaranthus tuberculatus), which we show to have undergone a massive expansion over the past century, with a contemporary effective population size estimate of 8 x 10⁷. We found variation at seven characterized TSR loci, two of which had multiple amino acid substitutions, and three of which were common. Th

SUBMITTER: Kreiner JM 

PROVIDER: S-EPMC8798060 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature