Circulating tumor DNA use in a community oncology practice.

ABSTRACT:

Background

This retrospective single center study aimed to describe circulating tumor DNA (ctDNA) comprehensive genomic profiling (CGP) utilization in a community practice for patients with advanced solid tumors.

Methods

All patients were included who were seen at the Scripps Hillcrest Oncology Clinic (San Diego, CA, USA) between September 2016 to March 2018 who had ctDNA assay testing performed. In this cohort, all ctDNA testing was performed to aid therapeutic decision making with wide variety in both the type of advanced solid tumor, as well as the line of therapy.

Results

Of the assays performed in the 41 patients included in this review, 42% of therapeutic actions following ctDNA assay results were influenced by the ctDNA result, including initiation of the corre

SUBMITTER: Chamberlain ED 

PROVIDER: S-EPMC8798503 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature