Identification of key protein-coding genes in lung adenocarcinomas based on bioinformatic analysis.

ABSTRACT:

Background

Lung cancer is one of the most common cancers and the primary cause of cancer-related deaths in the world. The 5-year survival of lung cancer patients is lower than 15%. As a common subtype of lung cancer, lung adenocarcinoma still has a high morbidity and mortality, although many strategies have been made, such as surgical operation, chemotherapy, targeted therapy. The use of gene expression microarray has provided a feasible and effective approach for the study on lung cancer. However, the biomarkers and potential therapeutic targets of lung adenocarcinomas are still not completely identified. Our study is aimed to find biomarkers and therapeutic targets of lung adenocarcinomas by identifying the key protein-coding gene in lung adenocarcinomas by bioinformatical approa

SUBMITTER: Yao R 

PROVIDER: S-EPMC8799172 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature