Sensitivity of the EQ-5D-5L for fatigue and cognitive problems and their added value in Q-fever patients.

ABSTRACT:

Purpose

Measuring health-related quality of life (HRQoL) with the EQ-5D-5L might lack sensitivity for disease-specific health complaints. This cross-sectional study analyzed whether fatigue and cognitive problems are captured by the EQ-5D-5L in a Q-fever patient population with persistent fatigue/cognitive problems, and whether addition of fatigue/cognition improved the explained variance for HRQoL.

Methods

A Dutch sample of Q-fever patients filled out the EQ-5D-5L and EQ VAS, the fatigue subscale of the Checklist Individual Strength, and a cognition dimension in the EQ-5D-5L format. The extent to which fatigue and cognition were captured by the EQ-5D-5L was determined based on distributional effects, head-to-head comparisons, Spearman rank correlation coefficients, and regr

SUBMITTER: Geraerds AJLM 

PROVIDER: S-EPMC8799410 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature