Comparison of paper-based nucleic acid extraction materials for point-of-care testing applications.

ABSTRACT: Cheap, rapid, simple and equipment-free nucleic acid extraction (NAE) is highly preferred for implementing nucleic acid detection at point-of-care (POC). Paper-based NAE materials have been extensively utilized due to their low cost, abundance, portability, biocompatibility and ease of chemical modification. However, it is challenging for users to choose the proper one from existing paper-based NAE materials for specific POC applications, which is determined by their physical and chemical properties. Additionally, building the relationship between the physical and chemical properties and the NAE efficiency of paper-based materials is instructive for development of new paper-based NAE materials. In this study, we first systematically compared the physical and chemical properties of six wide

SUBMITTER: Tang R 

PROVIDER: S-EPMC8799969 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature