Imaging somatosensory cortex responses measured by OPM-MEG: Variational free energy-based spatial smoothing estimation approach.

ABSTRACT: In recent years, optically pumped magnetometer (OPM)-based magnetoencephalography (MEG) has shown potential for analyzing brain activity. It has a flexible sensor configuration and comparable sensitivity to conventional SQUID-MEG. We constructed a 32-channel OPM-MEG system and used it to measure cortical responses to median and ulnar nerve stimulations. Traditional magnetic source imaging methods tend to blur the spatial extent of sources. Accurate estimation of the spatial size of the source is important for studying the organization of brain somatotopy and for pre-surgical functional mapping. We proposed a new method called variational free energy-based spatial smoothing estimation (FESSE) to enhance the accuracy of mapping somatosensory cortex responses. A series of computer simulations

SUBMITTER: An N 

PROVIDER: S-EPMC8800110 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature