A framework for research into continental ancestry groups of the UK Biobank.

ABSTRACT:

Background

The UK Biobank is a large prospective cohort, based in the UK, that has deep phenotypic and genomic data on roughly a half a million individuals. Included in this resource are data on approximately 78,000 individuals with "non-white British ancestry." While most epidemiology studies have focused predominantly on populations of European ancestry, there is an opportunity to contribute to the study of health and disease for a broader segment of the population by making use of the UK Biobank's "non-white British ancestry" samples. Here, we present an empirical description of the continental ancestry and population structure among the individuals in this UK Biobank subset.

Results

Reference populations from the 1000 Genomes Project for Africa, Europe, East Asia, and So

SUBMITTER: Constantinescu AE 

PROVIDER: S-EPMC8800339 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature