Bacteraemia caused by Lactobacillus rhamnosus given as a probiotic in a patient with a central venous catheter: a WGS case report.

ABSTRACT:

Introduction

Lactobacilli, especially Lactobacillus (L.) rhamnosus, are common and well-documented components of commercial probiotics [1]. Whole genome sequencing (WGS) is often used to compare bacterial genomes and their relatedness. In outbreak situations, it is used to investigate the transmission of pathogenic bacteria. WGS has also been used to determine safety in probiotics, by looking at potential virulence factors and resistance genes.

Case presentation

This case report describes a 56-year old multi-traumatised, immunocompetent woman who was given L. rhamnosus GG as a probiotic, and later developed a blood stream infection with L. rhamnosus GG.The patient was fed by a nasogastric tube, and she also had a central venous catheter for parent

SUBMITTER: Rubin IMC 

PROVIDER: S-EPMC8802096 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature