Remdesivir for pregnancy: A systematic review of antiviral therapy for COVID-19.

ABSTRACT:

Objective

The use of remdesivir for pregnant patients with coronavirus disease 2019 (COVID-19) showed conflicting results in prior studies. We aimed to systematically review its efficacy and safety for this population from the existing literature.

Methods

On July 26, 2021, registries (ClinicalTrials.gov) and databases (MEDLINE, ScienceDirect, Cochrane Library, JSTOR, DOAJ, and medRxiv) were systematically searched for research articles investigating remdesivir use in pregnant people with COVID-19. Clinical outcome, hospitalization duration, laboratory outcome, mortality, and adverse events were investigated.

Results

We obtained 13 observation studies with 113 pregnant people. In these studies, remdesivir improved the clinical condition of pregnant patients with COVID-

SUBMITTER: Budi DS 

PROVIDER: S-EPMC8802673 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature